Code	Reason for Stopping Treatment
1	Treatment failure (i.e. virological, immunological, and/or clinical failure
1.1	Virological failure
1.2	Partial virological failure
1.3	Immunological failure - CD4 drop
1.4	Clinical progression
1.5	Resistance (based on test result)
10	Hyperlactataemie/lactic acidosis
11	Bone toxicity
15	Social contra-indication
16	Contra-indication unspecified
16.8	Contra-indication expired
16.9	Contra-indication – other
17	MTCT regimen completed
18	Unwanted weight changes
2	Abnormal fat redistribution
3	Concern of cardiovascular disease
3.1	Dyslipidaemia
3.2	Cardiovascular disease
4	Hypersensitivity reaction (skin eruption etc.)
4.3	Injection site reaction
4.4	Injection fatigue (not related to safety)
5	Toxicity, predominantly from abdomen/G-I tract
5.1	Toxicity - GI tract
5.2	Toxicity - Liver
5.3	Toxicity - Pancreas
6	Toxicity, predominantly from nervous system
6.1	Toxicity - peripheral neuropathy
6.2	Toxicity - neuropsychiatric
6.3	Toxicity - headache
7	Toxicity, predominantly from kidneys
70	Pregnancy - toxicity concerns (during pregnancy)
75	Pregnancy - switch to a more appropriate regimen for PMTCT
8	Toxicity, predominantly from endocrine system
8.1	Diabetes
88	Death
9	Haematological toxicity (anemia etc.)
90	Side effects - any of the above but unspecified
90.1	Comorbidity
91	Toxicity, not mentioned above
91.1	Toxicity, unspecified
92	Availability of more effective treatment (not specifically failure or side effect related)
92.1	Simplified treatment available
92.2	Treatment too complex
92.22	Incorrect route of administration
92.3	Drug interaction
92.31	Drug interaction - commencing TB/BCG treatment
92.32	Drug interaction - ended TB/BCG treatment
92.33	Change in eligibility criteria (e.g. child old enough for tablets; refrigerator no longer available)
92.4	Protocol change
92.5	Regular treatment termination (used in tblMED e.g. for DAA's against HCV, antibiotics)
92.6	End of empiric treatment
92.7	Initiation of long-acting antiretroviral therapy
92.9	Change in treatment not due to side-effects, failure, poor adherence or contra-indication
92.91	Change to generic drug
92.92	Change to branded drug
93	Structured Treatment Interruption (STI)
93.1	Structured Treatment Interruption (STI) - at high CD4
94	Patient's wish/decision, not specified above
94.1	Non-compliance
94.2	Defaulter
94.3	Inability to come to injection
94.4	Long-acting treatment out of stock
94.5	Injection site adverse effect of long-acting injectable treatment
94.6	Personal decision to discontinue long-acting injectable treatment
94.7	Other reason for discontinuing long-acting injectable treatment, not described anywhere else
95	Physician's decision, not specified above
96	Pregnancy (see also more specific codes 70 and 75
96.1	Pregnancy intended
96.2	Pregnancy ended
97	Study treatment
97.1	Study treatment commenced
97.2	Study treatment completed
97.6	Drug not available
98	Other causes, not specified above
99	Unknown

Although most reasons mentioned above could be coded in ICD-10 codes, it is still certain that many reasons will never be defined in terms of ICD-10 (STI, physicians and patients decision), so to avoid a mixture of two different coding systems it is advised to go with the above list and build upon that for now. This coding list is identical to MED_RS used for non-ART medication recorded in tblMED