wiki:Hicdep_1.30/TableLabRes

Version 2 (modified by stels, 7 years ago) (diff)

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tblLAB_RES - Resistance testing

TODO
abstract for this table

Note: This table is tightly linked to tblLAB_RES_LVL_1, tblLAB_RES_LVL_2 and tblLAB_RES_LVL_3.

Resistance should be reported at lowest level of interpretation possible – so if the nucleotide sequence is available this should be reported rather than the list of mutations or resistance scores. However, the resistance test results should be captured if they have been part of the physician’s treatment decisions for the patient.

These four tables are designed to capture several possible formats the clinics and cohorts might have recorded resistance test data in. Once this data is gathered it should like all other tables be quality assessed. For the full nucleotide sequences a short guide on “Sequence Quality Control” can be found here:

TODO
fix the following link

http://hiv-web.lanl.gov/content/hiv-db/CONTAM/contam_main.html

Core fields

Note: Fields marked bold form the unique identifier for a record of the table.

  • PATIENT: Code to identify patient (Cohort Patient ID)
  • SAMP_ID: The assigned sample ID
  • SAMPLE_D: Date of the actual sample taken (NOT the test date)
  • SEQ_DT: Date and time when the sequencing was performed
  • LAB: Name of laboratory where the test was performed
  • LIBRARY: Library/algorithm used to identify resistance mutations
  • REFSEQ: Name/identifier of reference HIV strain used to find mutations
  • KIT: Vendor and version/name of the kit used for the test
  • SOFTWARE: Software and version used to determine resistance
  • TESTTYPE: Type of test
  • SUBTYPE: Subtype of HIV-RNA

Additional fields

TODO
it is somewhat unclear to me what should be captured here ~stels~