tblCANC - Diagnosis of Cancer


holds type and date of diagnosis of cancer

There is a large heterogeneity across cohorts regarding the documentation of cancer diagnoses. Some use ICD9 or ICD10 for cancer location and have no information on histology. Others have cross-linked with cancer registries and are able to provide very granular ICD-O-3 histology codes. There are also proprietary systems such as the NA-ACCORD short list (instructions, list_1 & list_2). In tblCANC we suggest to not restrict to a single coding system but to allow cohorts to provide the data in different systems as long as definitions and mapping tables are submitted alongside the data.

For new cohorts we propose to use ICD9/10 coding schemes for cancer location and ICD-O-3 for histology if these results can be obtained from cancer registries.
Each row of tblCANC consists of a diagnosis of one cancer type.
If AIDS defining cancers are reported in tblCANC they should NOT be deleted from tblDIS.

Core Fields

Note: Fields marked bold form the unique identifier for a record of the table.
Field name
Format
Description
character (or numeric if possible)
Patient id
yyyy-mm-dd
Date of diagnosis
character: see coding of date precision
optional precision annotation for date of diagnosis
character
Location code according to diagnosis
character
Location coding System: ICD10, ICD9, other systems, e.g. NA-ACCORD-short list
character
Histology code according to diagnosis
character
Histology coding system: ICD-O-3, other systems, e.g. NA-ACCORD-short list, None

Additional Fields

Field name
Format
Description

numeric:

  • 0 = No
  • 1 = Yes
  • 9 = Unknown
Diagnosis centrally adjudicated

numeric:

  • 0 = No
  • 1 = Yes
  • 9 = Unknown
Diagnosis histologically confirmed

numeric:

  • 0 = No
  • 1 = Yes
  • 9 = Unknown
Coding and Diagnosis taken from cancer registry

numeric:

  • 0 = No
  • 1 = Yes
  • 2 = Summary available
  • 9 = Unknown
Histology available
character
If HIST_AVAILABLE_Y = 1 or 2, please store a copy of the full report and provide a short free text histology summary here.

numeric:

  • 0 = No
  • 1 = Yes
  • 9 = Unknown
Has the patient previously received radiotherapy, chemotherapy or surgery for a malignant disease
yyyy
If yes, provide first year of treatment

QA Checks


TableCrosstableError CodeDescriptionStudy specificHICDEP?
AllTablesCrossTableATC001any date in database after DEATH_D in tblLTFU Yes
AllTablesCrossTableATC002any date in database after DROP_D in tblLTFU Yes
AllTablesCrossTableATC003any date in database before BIRTH_D in tblBAS Yes
AllTablesCrossTableATC004any date in database in the future Yes
AllTablesCrossTableATC005patients submitted previously who have been missed out Yes
AllTablesCrossTableATC006Any fields not coded as coding lists on table definition Yes